Ephedrine is a central nervous system stimulant used to treat breathing problems (as a bronchodilator), nasal congestion (as a decongestant), low blood pressure problems (orthostatic hypotension), or myasthenia gravis. This drug has also been used to treat certain sleep disorders (narcolepsy), menstrual problems (dysmenorrhea), or urine-control problems (incontinence or enuresis). Also used with diet plans for weight loss.
The most common side-effects of ephedrine are tachycardia, anxiety, nausea, restlessness, and insomnia. Tremor, dry mouth, impaired circulation to the extremities, hypertension, headache, and cardiac arrhythmias may occur.
The symptoms of overdose are normally seen as nausea, vomiting, hypertension, fever, palpitations, tachycardia, restlessness, respiratory depression, and convulsions. Paranoid psychosis, delusions, and hallucinations may also follow ephedrine overdosage.
In severe overdosage, the stomach should be emptied by emesis and lavage. Management is by supportive symptomatic therapy.
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